Soft ROCK Inhibition as Novel Treatment Mechanism for Glaucoma
نویسندگان
چکیده
Glaucoma is a leading cause of irreversible blindness. The most common form of glaucoma is Primary Open Angle Glaucoma (POAG), which affects more than 2 million persons over 40 years of age in the USA alone1. Elevated intraocular pressure (IOP) is the only proven treatable risk factor in multiple forms of glaucoma including POAG2. A number of IOP-lowering agents are therefore used in clinical practice. However, the majority of these agents do not improve the outflow of aqueous humor through the trabecular meshwork3, which represents an important component of elevated IOP (Figure 1).
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